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Results for "

Brexpiprazole-d<sub>8</sub>

" in MedChemExpress (MCE) Product Catalog:

2

Inhibitors & Agonists

2

Isotope-Labeled Compounds

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-15780S
    Brexpiprazole-d8

    OPC-34712-d<sub>8sub>

    		 5-HT Receptor Dopamine Receptor Neurological Disease
    Brexpiprazole-d8 is a deuterium labeled Brexpiprazole (OPC-34712). Brexpiprazole, an atypical antipsychotic agent, is a partial agonist of human 5-HT1A and dopamine receptor (Ki=0.12 nM and 0.3 nM, respectively). Brexpiprazole is also a 5-HT2A receptor antagonist (Ki=0.47 nM)[1][2].
    Brexpiprazole-d8
  • HY-15780S1
    Brexpiprazole-d8-1

    OPC-34712-d<sub>8sub>-1

    		 Dopamine Receptor Adrenergic Receptor 5-HT Receptor Neurological Disease
    Brexpiprazole-d8-1 is the deuterium labeled Brexpiprazole[1]. Brexpiprazole (OPC-34712), an atypical orally active antipsychotic agent, is a partial agonist of human 5-HT1A and dopamine D2L receptor with Kis of 0.12 nM and 0.3 nM, respectively. Brexpiprazole is also a 5-HT2A receptor antagonist with a Ki of 0.47 nM. Brexpiprazole also shows potent antagonist activity at human noradrenergic α1B (Ki=0.17 nM) and α2C receptors (Ki=0.59 nM)[2][3].
    Brexpiprazole-d8-1

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